Grants Awarded
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 Grand Challenges Explorations Grants

Grand Challenges Explorations fosters creative projects that show great promise to improve the health of people in the developing world. Grants target an expanding set of global health topics, and there are two award rounds per year. Projects with demonstrated success in their initial phase of research have the opportunity to receive Phase II funding of up to $1 million.

On June 3, 2014, 52 researchers were awarded new Grand Challenges Explorations grants. Read more about these below. In addition, 3 Explorations projects were awarded Phase II funding. To read more about these new Phase II grants, select "Phase II" in the Grant Phase drop-down menu, while showing all topics and all rounds.

To review all Explorations projects, select “Show All Topics” in the Topic drop-down menu, "Show All Rounds" in the Date and Grant Round drop-down menu, and “Show All Phases” in the Grant Phase drop-down menu.

Date and Grant Round
Grant Phase
Showing Grants 1 to 1 of 1
Unleashing Protein Disaggregases to Prevent HIV Infection
Primary Investigator:
James Shorter, University of Pennsylvania, Philadelphia, PA, United States - US
Round 4 – May 2010
Phase I
James Shorter of The University of Pennsylvania in the U.S. will engineer enzymes that disassemble protein fibrils found in semen, which are known to allow for the transmission of HIV infection. The ability to reverse fibril formation could block sexual transmission of HIV and provide a new weapon against the global HIV/AIDS pandemic.

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