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PRIMARY INVESTIGATOR:

Dr. Peter Singer, University of Toronto, Toronto, Ontario, Canada - CA
Dr. James Lavery, St. Michael's Hospital, Toronto, Ontario, Canada - CA

Addressing Ethical, Social and Cultural Issues related to the Grand Challenges in Global Health
Project Progress & Milestones Collaborators
Project

To best ensure successful completion of large-scale research projects and the appropriate adoption of technologies that arise from their projects, investigators working in global health must pay attention not only to science, but to the ethical, social, and cultural issues that surround their work. These ethical, social, and cultural concerns have become increasingly important to the success of projects undertaken in the developing world, including many of the projects funded by Grand Challenges in Global Health. To assist Grand Challenges in Global Health investigators, Drs. Singer and Lavery and their colleagues are providing advisory services on ethical, social, and cultural issues related to research in the developing world. In addition, their project aims to help foster the successful and appropriate adoption by communities in need of technologies that result from Grand Challenges in Global Health projects.

The project team's advisory service for Grand Challenges investigators is in place, and work has begun to plan for the successful adoption of technologies that may arise from Grand Challenges in Global Health projects. The project team is currently conducting two global case studies, one on community engagement in research in the developing world and the other on commercialization of health products in low-resource settings. The case studies will identify good practices in both areas.

Because 10 Grand Challenges in Global Health projects are relevant to malaria, the project team is developing an Internet-based public engagement module on the disease, aimed at increasing awareness of malaria among young people and providing them with opportunities to take action. "MalariaEngage" will include technology allowing users to make financial contributions to support malaria research projects in the developing world.

Project Progress & Milestones:
Conducted 24 in-depth consultations with Grand Challenges investigators to develop and implement approaches to the ESC issues specific to their projects. The advisory service team has used these consultations to develop solutions and strategies to deal with issues affecting not only other Grand Challenges in Global Health projects, but research in the developing world in general.
Published four working papers in the journal PLoS Medicine, including reviews of community engagement and the role of civil society organizations in research in the developing world. Investigators have published one paper on the development and adoption of health technologies in the journal Nature.
Established four working groups made up of Grand Challenges in Global Health investigators working in the areas of vaccines, genetic control of vectors, nutritionally enhanced foods, and diagnostics. The working groups will identify barriers to adoption of each specific technology and commission research to address these barriers.
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Collaborators:
Durban, South Africa - ZA
Pune, India - IN
Navrongo, Ghana - GH
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