Skip Navigation LinksHome > The Grand Challenges > Grand Challenge #15
CHALLENGE 15:
Discover Biomarkers of Health and Disease

Background
High-throughput approaches to genomics, proteomics, and metabolomics have identified diverse candidate biomarkers of health and disease. Validated biomarkers coupled with new technologies for miniaturization and highly parallel detection could enable radically new ways to diagnose health and disease states in an individual, even in remote or impoverished settings.

Roadblock
Lack of accurate and sensitive biomarkers appropriate for point-of-care assessment tools in the developing world means that many health risks and illnesses remain poorly defined and receive inappropriate treatment. In addition, little information about the burden of disease is available to guide population health decisions.

Challenge
To discover and validate biomarkers for use in simple, low-cost tests appropriate for achieving definitive point-of-care assessment of health and disease states in individuals in developing world settings.

Projects

BIOMARKERS OF TUBERCULOSIS - FEBRUARY 2012
BIOMARKERS OF GUT FUNCTION - DECEMBER 2012
 

 Map of Grants